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It features five key nutrients that are involved \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003ein homocysteine metabolism: folate as calcium folinate and Quatrefolic\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e® \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003efor increased bioactivity; \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003etrimethylglycine; and vitamins B12, B6, and B2. 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